With a commitment to improving the prognosis of heart valve diseases, Aptus Bioreactors provides novel bioreactor systems and accessories capable of creating and testing living, patient-specific, tissue engineered heart valves (TEHVs). Using the TEHVs, we envision “One Surgery, for Life” where hospital costs, risks, and other burdens associated with heart valve disease are eliminated.
Please join us in making this a reality!
The Platform Heart Valve Bioreactor provides the base system used to test and develop heart valves under physiological conditions. This system is used for preconditioning valve scaffolds, pre-clinical testing of tissue development, durability, and hemodynamic compatibility, and the testing of cardiovascular implants on heart valves. Using additional accessories, the bioreactor system can be used to replace early stage animal models or in vitro models for studying valve physiology, pathology, and patient-specific theranostics.
The Rotating Cell Seeder is to be used in the development of novel tissue engineered heart valves by allowing for location-specific cell seeding to heart valve roots. The device provides control over rotation style and speed, is autoclavable for repeated use, and provides gas exchange in a sterile in vitro environment.
The Vascular Bioreactor features peristaltic pump technology combined with a highly-developed system of reservoirs, valves, and tubing to create a fully-tunable range of cardiovascular conditions. It can be used for conditioning, decellularization, or re-seeding in an open or sterile environment. This system is available in both standard and scalable versions.
Aptus Quick Connect Fittings were developed in a bioengineering lab around the ideology of simplifying the installation, changing, and cleaning of connections. Our solution is a single-piece quick-action fitting that installs with a simple push. Since the connection is not threaded, it eliminates the need for traditional tape sealing methods.
The MechAnnulus (TM) Valve Mount is a secure and easy system to hold heart valves in place during seading and conditioning of heart valves including biological, bioprosthetic, and mechancial heart valves.
The Compliance and Burst Pressure Module is a multi-user control and conditioning hardware that is the core equipment utilized in a number of modular extensions for various tissue testing and culturing purposes. The module is a vital part of the tissue-testing process for determining specific mechanical properties of tubular tissues.
